Geodon (Anti Depressants)

Geodon (Anti Depressants)

Monday, January 4, 2010

Clinical Pharmacology 3

Metabolism and Elimination: Ziprasidone is copiously transformed by metabolism after the oral administration with only a small quantity excreted in the urine (<1 style="font-weight: bold;">Intramuscular Pharmacokinetics Systemic
Bioavailability: the bioavailability of ziprasidone constituent is intramusculairement 100 %. After the intramuscular administration of simple doses, maximum concentration of serum occurs typically in about post dose 60 minutes or earlier and medium half-life (T ½) vary from two to five hours. The increase of exhibition in a way linked by the dose and further to three days of intramuscular proportion, not enough accumulation is noticed.

Metabolism and Elimination: Although the metabolism and the elimination of IM ZIPRASIDONE are not systematically assessed, they would not expect what in the intramuscular road of administration change the tracks of the metabolism.

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